Efficacy and Safety of Nalbuphine Versus Pethidine in Oocyte Retrieval: A Randomized controlled trial
Phase 4
- Conditions
- Efficacy of Nalbuphine Versus Pethidine in Oocyte retrievalNalbuphine,Pethidine,Midazolam,Oocyte retrieval, pain
- Registration Number
- TCTR20240406003
- Lead Sponsor
- Faculty of Medicine, Chulalongkorn University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- Female
- Target Recruitment
- 100
Inclusion Criteria
1. Female age 18 to 48 years
2. Wants to undergo oocyte retrieval process for ARTs such as IVF/ICSI or social freezing
Exclusion Criteria
1. Active liver disease or uncontrolled asthma
2. Allergic to Nalbuphine, Pethidine, Midazolam
3. Less than 3 follicles on ultrasound
4. History of Monoamine oxidase inhibitors (MAOIs) or Tricyclic antidepressant use in 2 weeks before the procedure
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain score within 6 hours after intervention Visual analogue scale
- Secondary Outcome Measures
Name Time Method Side effects within 24 hours after intervention Patient reported using a questionnaire interview,Patient cooperation score during the procedure Operator reported using a questionnaire interview,Quality of egg retrieved after the oocyte retrieval percent of MII egg retrieved. counted by experience medical lab personnel