Comparison efficacy of olanzapine when added to nutritional weight gain improvement in advanced cancer patients receiving chemotherapy: A randomized placebo-controlled trial
Phase 2
- Conditions
- Advanced stage cancer who will receive chemotherapy treatmentOlanzapine, weight gain, quality of life, anorexia,
- Registration Number
- TCTR20240524004
- Lead Sponsor
- Rajavithi hospital, Thailand
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
1. Advanced stage cancer who will receive chemotherapy treatment
2. Age>= 18 years
3. ECOG 0-2
4. Life expectancy > 3 months
5. Sign inform consent
Exclusion Criteria
1. Concurrent chemoradiation
2. Receiving other antidepressants or antipsychosis
3. NG, NJ tube insertion
4. Corticosteroids treatment more than 1 months
5. Megestrol acetate treatment
6. Pregnancy or breastfeeding
7. Olanzapine allergy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method weight gain 12 weeks weight change measurement kilogram record by SaintMed super smart society 5.0 machine by patient self-standing then recording by nurse aid
- Secondary Outcome Measures
Name Time Method Quality of life 12 weeks EORTC QLQ-C30,Anorexia 12 weeks VAS scale/FAACT A/CS