The predictive role of markers in COVID-19 patients and it’s co-relationship with spo2/fio2and pao2/fio2 ratio,a retrospective observational study in Tertiary care covid ICU
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 250
- 试验地点
- 1
- 主要终点
- To identify the level of markers determining outcome of COVID 19 patient
研究概览
简要总结
Although it is a known fact that inflammation is caused by infectious diseases, and growing evidence supports its significant role in the progression of various viral pneumonia, including COVID-19 [7]. Severe inflammatory responses contribute to weak adaptive immune response, thereby resulting in immune response imbalance. Therefore, circulating biomarkers that represent inflammation and immune status are known potential predictors for the prognosis of COVID-19 patients [8]. Peripheral white blood cell (WBC) count, neutrophil (NEU)-to-lymphocyte (LYM) ratio (NLR), derived NLR ratio (d-NLR, neutrophil count divided by the result of WBC count minus neutrophil count), platelet-to-lymphocyte ratio (PLR) and lymphocyte-to-monocyte ratio (LMR),interleukin 6 are indicators of the systemic inflammatory response [9] that are widely investigated as useful predictors for the prognosis of patients with viral pneumonia. By collecting the data from confirmed cases, we will attempt to determine the effect of sex, age, CRP, WBC count, NLR, LMR, PLR, and co morbidities on the prognosis of patients with COVID-19 pneumonia and it’s corelation with lungs oxygenation.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)(—)
- 性别
- All
入选标准
- •all covid Patient.
排除标准
- •non covid Patient Excluded.
结局指标
主要结局
To identify the level of markers determining outcome of COVID 19 patient
时间窗: baseline,at 1day,3day,6 day ,7 day
次要结局
- To find the correlation between SpO2/FiO2 and markers for progression of severity of COVID(To find the co-relationship between PaO2/FiO2 and markers for progression of severity of COVID.)
