Clinical Evaluation of Treatment With Micro-surgical Management of Type I Multiple Gingival Recessions Using Coronally Advanced Flap With Either Advanced Platelet-Rich Fibrin or Concentrated Growth Factor: A Comparative Analysis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Growth Factors, Combined Defect of
- Sponsor
- Bulent Ecevit University
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Complete and mean root coverage
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
The purpose of this study was to compare and evaluate the clinical effects of Concentrated Growth Factor (CGF) and Advanced Platelet-Rich Fibrin (A-PRF) applied together with Coronally Advanced Flap (CAF) technique using a microsurgical approach in the treatment of Type I multiple gingival recessions (GR).
Investigators
Figen Öngöz Dede
Clinical Association Professor
Bulent Ecevit University
Eligibility Criteria
Inclusion Criteria
- •Systematically and periodontally healthy non-smokers
- •Presence of Cairo Recession type I gingival recession with ≥ 2 mm gingival recession depth, probing depth \<3 mm and gingival thickness (GT) ≥ 0.8 mm on both sides of the maxillary arch
- •Width of keratinized gingiva ≥ 2mm
- •Presence of identifiable cemento-enamel junction
- •Full-mouth plaque index (PI) \< 20 %
- •Gingival index (GI) scores =1
- •Presence of tooth vitality
- •Absence of caries, restorations and furcation involvement in the treated area
Exclusion Criteria
- •Patients who had systemic problems that wound contraindicate for periodontal surgery
- •Usage of medications known to interfere with healing and to cause gingival enlargement
- •Recession defects associated with demineralization, deep abrasion, previous surgery in the defects area within the past 1 year
- •Pregnant or lactating females
- •Drug and alcohol abuse
Outcomes
Primary Outcomes
Complete and mean root coverage
Time Frame: Change from baseline at 6 months of the percent of complete and mean root coverage
Percentages of root coverage and complete root coverage were calculated according to the following standard formulae. Percentage of root coverage: \[(preop. vertical gingival recession (VGR)- postop.VGR)\\ preop. VGR\] x 100 Percentage of complete root coverage: \[(teeth with complete root coverage) \\ (all treated teeth)\] x 100.
Secondary Outcomes
- Hypersensitivity score (HS)(Change from baseline at 6 months of the hypersensitivity score)
- Keratinized gingiva width (WKG)(Change from baseline at 6 months of keratinized gingiva width)
- Gingival thickness(Change from baseline at 6 months of the gingival thickness)
- Patient esthetic score (PES)(Change from baseline at 6 months of the patient esthetic score)
- Patient comfort score (PCS)(Change from baseline at 6 months of the patient comfort score)