The Impact of Zinc and Probiotics in Preventing Pediatric Antibiotic-Associated Diarrhea in Southern Iran

Not Applicable

Completed

• Conditions: Antibiotic-associated Diarrhea; Diarrhea

• Registration Number: NCT06665503
• Lead Sponsor: Hormozgan University of Medical Sciences

Brief Summary

The Impact of Zinc and Probiotics in Preventing Pediatric Antibiotic-Associated Diarrhea in Southern Iran

Detailed Description

The participants will be children aged 3 months to 3 years.The zinc group received oral zinc supplementation; 2.5 ml every 12 hours for children aged \<1 year and 5 ml every 12 hours for older children; the probiotics group received oral probiotics; 1 probiotic sachet; and the control group received nothing.

Study Timeline

• Study Start: 2020-09-01
• Primary Completion: 2021-03-01
• Study Completion: 2021-05-01
• Status Verified: 2024-10
• Study First Submitted: 2024-10-29
• Study First Submitted QC: 2024-10-29
• Study First Posted: 2024-10-30
• Last Update Submitted: 2024-11-08
• Last Update Posted: 2024-11-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 165

Inclusion Criteria

1. children aged 3 months to 3 years
2. prescribed antibiotics for various medical conditions

Exclusion Criteria

1. Diarrhea, Dysentery
2. Underlying chronic disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Rate of Antibiotic-Associated Diarrhea	6 month	Passing loose, watery stools three or more times a day after taking antibiotic by questionnaire.

Trial Locations

Locations (1)

Hormozgan University of Medical Sciences; 🇮🇷 Bandar Abbas, Hormozgan, Iran, Islamic Republic of