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临床试验/NCT00186433
NCT00186433已完成不适用

A Longitudinal Study of Plasma EBV DNA in Nasopharyngeal Carcinoma From Both Endemic and Non-Endemic Patient Populations

Stanford University1 个研究点 分布在 1 个国家目标入组 49 人开始时间: 2001年11月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
49
试验地点
1
主要终点
Plasma Epstein-Bar Virus (EBV) DNA concentrations

研究概览

简要总结

  1. To determine the prognostic implication of plasma Epstein-Bar Virus (EBV) DNA concentrations, as measured by quantitative polymerase chain reaction (PCR) in patients with nasopharyngeal carcinoma (NPC).
  2. To relate pretreatment plasma EBV DNA concentration to WHO classification of these tumors both in endemic and non-endemic areas.
  3. To determine whether pretreatment plasma EBV DNA can serve as a prognostic factor for both endemic and non-endemic patient populations.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Having a new diagnosis of Nasopharyngeal carcinoma.
  • Being treated with either radiotherapy or chemoradiotherapy for this condition.

排除标准

  • Age <18 since NPC is a very rare condition in this age group and may have a different biological behavior
  • Patients who are unable to provide informed consents for themselves.

结局指标

主要结局

Plasma Epstein-Bar Virus (EBV) DNA concentrations

时间窗: every 6 months until end of study

measured by quantitative polymerase chain reaction (PCR)

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Quynh-Thu Le

Katharine Dexter McCormick and Stanley McCormick Memorial Professor

Stanford University

研究点 (1)

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