Comparative Study on the Value of Three DWI Scan Sequences of 3.0T Magnetic Resonance in Staging of Gastric Cancer
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Enrollment
- 129
- Locations
- 1
- Primary Endpoint
- T staging of gastric cancer
Study Overview
Brief Summary
Accurate staging is critical for effective gastric cancer treatment planning. Conventional DWI (C-DWI) has limitations in image quality due to magnetic field inhomogeneity, which hampers precise T staging.
This study aims to compare the image quality and T staging accuracy of C-DWI, TSE-DWI, and ZOOMit-DWI (Z-DWI) sequences in MRI examinations of gastric cancer patients.
A prospective study plan to enroll 72 gastric cancer patients undergoing preoperative MRI with C-DWI, TSE-DWI, and Z-DWI sequences using a 3.0 T scanner. Quantitative metrics (ADC, SNR, CNR) and image quality were evaluated. T staging accuracy was assessed by comparing MRI results with postoperative pathological staging using ROC analysis.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Diagnostic
- Masking
- Double (Participant, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 80 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •The patient was diagnosed with gastric cancer by pathological biopsy
- •No biopsy was taken within 1 week before MR Examination to rule out the effect of bleeding on the image
- •No contraindications for MRI examination; And exclude serious heart, liver, kidney, cerebrovascular diseases.
Exclusion Criteria
- •The image quality cannot meet the diagnostic criteria;
- •Patients could not tolerate MRI examination, resulting in incomplete MR-related sequence image data.
Arms & Interventions
SS-EPI-DWI T-stage of gastric cancer
TSE-DWI T-stage of gastric cancer
Intervention: Scanning parameter (Diagnostic Test)
ZOOM-DWI T-stage of gastric cancer
Intervention: Scanning parameter (Diagnostic Test)
Outcomes
Primary Outcomes
T staging of gastric cancer
Time Frame: one year
Study on the value of three DWI scanning sequences in T staging of gastric cancer
Secondary Outcomes
No secondary outcomes reported