Novel Equation for Estimating Intraperitoneal Pressure

Completed

• Conditions: Intraperitoneal Pressure; Peritoneal Dialysis; Equation

• Registration Number: NCT05313841
• Lead Sponsor: Peking University First Hospital

Brief Summary

Intraperitoneal Pressure is associated with the complications of increased intra-abdominal pressure in peritoneal dialysis patients. Due to the complicated operations, routine measurement of hydrostatic intraperitoneal pressure is not used routinely in adult peritoneal dialysis patients. There ars some limitions in equations from previous studies, such as the sample size was small , and the study population was limited. In the study, we aim to develop and validate an equation for estimating intraperitoneal pressure in peritoneal patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-07-17
• Primary Completion: 2021-10-31
• Study Completion: 2021-10-31
• Status Verified: 2022-03
• Study First Submitted: 2022-03-29
• Study First Submitted QC: 2022-03-29
• Last Update Submitted: 2022-03-29
• Study First Posted: 2022-04-06
• Last Update Posted: 2022-04-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Peritoneal dialysis patients
• Dialysis length >1 month
• Aged 18-80 years
• Injection volume of peritoneal dialysis solution>1500ml

Exclusion Criteria

• Acute complications （ peritonities, cardiovascular and cerebrovascular diseases) to hospitalization 1 month prior to the study
• History of abdominal surgery and trauma 1 month prior to the study
• Previous history of hernia, leakage, or thoracoabdominal fistula
• Can't come for a follow-up visit

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Novel equation development	July 17, 2021 to September 30, 2021	Developed equation for estimating intraperitoneal pressure in peritoneal dialysis patients
Novel equation validation	October 1,2021 to October 31,2021	Validate the novel equation with intraperitoneal pressure obtained by Durand method

Trial Locations

Locations (1)

Jie Dong; 🇨🇳 Beijing, Beijing, China