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Clinical Trials/NCT04682275
NCT04682275
Completed
Not Applicable

Gender Differences in Periodontal Status of Depressive and Non-Depressive Individuals

Necmettin Erbakan University1 site in 1 country339 target enrollmentFebruary 12, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Periodontal Diseases
Sponsor
Necmettin Erbakan University
Enrollment
339
Locations
1
Primary Endpoint
Depression level
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

There is a relationship between depression and periodontal disease. This relationship may be double-sided. A psychological state such as anxiety, depression, body image, and self-esteem may be affected from the symptoms of periodontal disease.

Detailed Description

Background: Depression is a multifactorial disease characterized by a variety of symptoms. Individuals with psychiatric disorders seem to be more prone to periodontitis. However periodontal disease and depression can be considered bidirectional risk factors. Periodontal diseases can also be an effect on depression. The purpose of the present study was to evaluate the gender-related differences in the relationship between periodontal diseases and depression in male and female adults. Material and methods: The study population consisted of 339 subjects. Two groups were formed from these patients: 171 females with periodontal disease (71 subjects with gingivitis, 100 subjects with periodontitis); 168 males with periodontal disease (72 subjects with gingivitis, 96 subjects with periodontitis). Clinical periodontal and psychological measures were performed on females and males group.

Registry
clinicaltrials.gov
Start Date
February 12, 2017
End Date
February 12, 2018
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Fatma Uçan Yarkaç

Principal Investigator

Necmettin Erbakan University

Eligibility Criteria

Inclusion Criteria

  • the presence of periodontal diseases

Exclusion Criteria

  • the presence of any systemic disease other than depression
  • smoking and alcohol consumption
  • the use of any drugs (antidepressants, anti-inflammatory, and antimicrobial medicaments, and hormonal supplements) that affect the periodontal condition
  • have received any periodontal treatment in the last six months
  • hormonal condition such as pregnancy or lactation

Outcomes

Primary Outcomes

Depression level

Time Frame: Baseline

The differences in depression level between females and males. Depression level was determined using the Beck Depression Inventory. Beck Depression Inventory (BDI) consists of 21 items. Each of the 21 statements is scored from 0 to 3. The total score allows the classification of depression severity. Scores less than 10 indicates lack of the depression. The scores between10-16 indicate minimum depression, the scores between17-29 indicate moderate depression, scores greater than 30 indicate severe depression.

Secondary Outcomes

  • Gingival index(Baseline)
  • Probing pocket depth(Baseline)
  • Bleeding on probing(Baseline)
  • Plaque index(Baseline)

Study Sites (1)

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