Effect of Stent Placement on Short Term Survival of Left Sided Obstructive Colorectal Cancers
- Conditions
- Colorectal Cancer
- Interventions
- Procedure: Self-Expandable Metallic Stent Placement
- Registration Number
- NCT06437691
- Lead Sponsor
- Yasir Musa Kesgin, MD
- Brief Summary
The aim of this observational study is to determine effect of stent placement on survival results in first three years in a patient who applied to the emergency department with obstruction due to colorectal cancer. Eligible patients divided into two groups. Group A includes patients underwent emergency surgery directly. Patients underwent elective surgery following stent placement as bridge-to-surgery. Patients underwent elective surgery following bridge-to-surgery stent placement were accepted as Group B.
- Detailed Description
Patients who applied to emergency department of a single tertiary referral center between January 2016 and December 2020 and diagnosed as left sided obstructive colorectal cancer were included in this retrospective study. All patients were equal or older than 18 years and histopathologically found to have primary colorectal malignant neoplasms.
Patients were excluded from the analysis if they met any of the following criteria:
* Who underwent emergency surgery due to unsuccessful stent application intervention or stent-related complications developed,
* Those with middle and lower rectum tumors or received neoadjuvant treatment,
* Perforation,
* Who underwent subtotal or total colectomy (as a result of colon ischemia in the cecum, microperforation, etc.),
* Recurrent disease patients
* Patients have metastasis
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 65
- All patients were equal or older than 18 years and histopathologically found to have primary colorectal malignant neoplasms and diagnosed as left sided (descending colon, sigmoid colon and upper rectum) obstructive colorectal cancer were included
- Who underwent emergency surgery due to unsuccessful stent placement intervention
- Who underwent emergency surgery due to stent-related complications
- Those with middle and lower rectum tumors
- Those received neoadjuvant treatment,
- Patients have perforation,
- Who underwent subtotal or total colectomy (as a result of colon ischemia in the cecum, microperforation, etc.),
- Who has a recurrent disease or metastasis.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Group B - Stent Group Self-Expandable Metallic Stent Placement Left sided obstructive colorectal cancer patients underwent elective surgery following decompression via self-expandable metallic stent placement.
- Primary Outcome Measures
Name Time Method Disease Free Survival 3 years The local or systemic recurrence free time period of patient after being diagnosed as colorectal cancer after coming to emergency department
Overall Survival 3 years The survival time of patient after being diagnosed as colorectal cancer after coming to emergency department
- Secondary Outcome Measures
Name Time Method Serious complications 90 days Postoperative complications of patients that have a Clavien-Dindo Score greater than or equal to 3
Minimally invasive surgery 90 days Patients that found a chance for fully minimally invasive surgery for resection of colorectal cancer
End colostomy rate 90 days Patients that have a end colostomy at the end of surgical resection of colorectal cancer
Mortality 90 days Death of patient in postoperative first three months