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Transitional Care Program for Fluid Overload in Cirrhosis

Not Applicable
Recruiting
Conditions
Cirrhosis, Liver
Interventions
Behavioral: Transitional Care Program
Registration Number
NCT06174272
Lead Sponsor
Milton S. Hershey Medical Center
Brief Summary

The goal of this clinical trial is to learn about an intensive monitoring plan (transitional care program) in patients with cirrhosis and excessive swelling that are going to be discharged from the hospital.

The main question\[s\] it aims to answer are:

* How much time and what resources are needed to run such a program

* How well do patients follow up with the phone calls, bloodwork, and doctor appointments?

* Do the patients enrolled in the program have less need for hospitalization later, less kidney injury, better fluid control, and/or better survival compared to patients that are not in the program?

Participants will

* Be given a digital scale and a binder with educational material and a log to monitor their weights after discharge from the hospital

* Receive a phone call from the study team within 72 hours of discharge and weekly

* Be given a follow up appointment with hepatology within 4 weeks of discharge

Researchers will compare participants in this program to patients that receive normal care to see if there are differences in need for hospitalization later, kidney injury, fluid control, and/or survival.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
20
Inclusion Criteria
  • Patients > 18 years of age.
  • Inpatient at Penn State Health, Milton S. Hershey Medical Center.
  • Diagnosis of cirrhosis.
  • Hospitalized with fluid overload (ascites and/or significant anasarca/edema) requiring diuretic therapy.
  • English speaking
Exclusion Criteria
  • Placement of a TIPS.
  • Ascites from an etiology other than cirrhosis, such as malignancy, heart failure, pancreatitis, nephrotic syndrome.
  • Non-English speaking

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Transitional Care ProgramTransitional Care ProgramParticipants will receive a digital scale and monitoring log, educational material, a phone call within 72 hours of discharge and weekly for 8 weeks, and a follow up appointment with a hepatologist within 4 weeks of discharge.
Primary Outcome Measures
NameTimeMethod
Number of instances of weight monitoring8 weeks for each participant

at home monitoring weight

feasibility of the programall 8 weeks of each participant

how much time does it take to review material and complete phone calls

Number of follow up visits8 weeks for each participant

lab visits, primary care visits, hepatology visits

Number of successful phone calls8 weeks for each participant

weekly phone call with participant

Secondary Outcome Measures
NameTimeMethod
Number of subjects that develop Acute Kidney Injury12 months

Creatinine increase of \>0.3g/dL

Number of Hospitalizations per participant12 months

number of admissions to the hospital

Number of subjects that continue to have volume overload12 months

persistent weight above dry weight and/or ongoing ascites/lower extremity edema/pleural effusion

Number of subjects that expire12 months

subject death

Trial Locations

Locations (1)

Penn State Milton S. Hershey Medical Center

🇺🇸

Hershey, Pennsylvania, United States

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