Bowel plus anastomotic perfusion and oxygenation in colorectal surgery: variables to predict anastomotic leakage?

Recruiting

• Conditions: darmperfusie en naadlekkage; blood flow; bowel perfusion

• Registration Number: NL-OMON32021
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 210

Inclusion Criteria

1. patients undergoing the following surgery: left or right hemicolectomy, simoid resection, anterior resection or partial small bowel resection with primary anastomosis.
2. age 18 years and older
3. surgery at VU medical center
4. oral and written informed consent

Exclusion Criteria

1. no informed consent
2. palliative surgery
3. emergency surgery

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary study parameters<br /><br>-oxygen saturation of haemoglobin at anastomosis including systemic saturation<br /><br>level.<br /><br>-relative amount of haemoglobin at anastomosis including systemic haemoglobin<br /><br>level.<br /><br>-blood flow at anastomosis site.<br /><br>-blood velocity at anastomosis site.<br /><br>-functional recovery of perfusion and oxygenation at the anastomosis after<br /><br>reperfusion.<br /><br><br /><br><br /><br>Primary study outcomes<br /><br>-clinical signs of anastomotic leakage, objectified by abdominal CT scan.<br /><br>-stricture at site of anastomosis</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>none applicable</p><br>