Rectal Mucosal Perfusion and Oxygenation in Patients with Rectal Cancer; Variables to Predict Response to Radiation Therapy and Anastomotic Leakage?

• Conditions: rectal cancer; rectal carcinoma; 10017991

• Registration Number: NL-OMON32076
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 28

Inclusion Criteria

1. Patients undergoing neoadjuvant radiation therapy at the VU University medical center for rectal cancer.
2. age 18 years and older
3. informed consent

Exclusion Criteria

1. no informed consent
2. palliative treatment

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>-Correlation between perfusion and oxygenation in tumor and rectal mucosa and<br /><br>downgrading of the tumor.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>-Radiation therapy induced changes in the perfusion and oxygenation of the<br /><br>rectal mucosa.<br /><br>-Correlation between rectal mucosal perfusion and oxygenation and anastomotic<br /><br>leakage. </p><br>