Study to find if weight loss surgery affects the symptoms of heartburn and vomiting
Not Applicable
- Conditions
- Health Condition 1: E662- Morbid (severe) obesity with alveolar hypoventilation
- Registration Number
- CTRI/2019/06/019705
- Lead Sponsor
- ADY HARDINGE MEDICAL COLLEGE
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1) Patients with morbid obesity of both genders, aging between 18 and 65 years will be included.
2) Patients with a body mass index (BMI) > 40 kg/m² or BMI > 35 kg/m² with obesity related comorbidities ( metabolic syndrome, Type 2 Diabetes Mellitus , Non alcoholic fatty liver disease, hyperlipidemia ,Hypertension and sleep apnea)
Exclusion Criteria
1) Patients who underwent previous bariatric surgery or upper gastrointestinal surgeries.
2) Patients with secondary obesity due to endocrine or metabolic diseases
3) Patients with psychiatric disorders
4) Patient with deep venous thrombosis.
5) Patients with Peptic ulcer disease, achlasia cardia.
6) Patients unfit for general anaesthesia.
7) Patients lost to follow up.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Gastroesophageal reflux ( GER ) before and 3 months after Laparoscopic Sleeve Gastrectomy ( LSG ) using 24 hour Multichannel Intraluminal Impedance (MII) pH monitoring in morbidly obese patientsTimepoint: Before and 3 months after surgery
- Secondary Outcome Measures
Name Time Method i.Excess weight loss after laparoscopic sleeve gastrectomy at 3 months duration. <br/ ><br>ii.Non-acidic reflux before and 3 months after Laparoscopic Sleeve Gastrectomy <br/ ><br>iii.To corelate MII pH manometery with Upper GI Endoscopy and GERD-Q scoring in morbidly obese patients undergoing Laparoscopic Sleeve Gastrectomy <br/ ><br>Timepoint: Before and 3 months after Surgery