To study the occurrence of stomach insufflation with air while administering general anaesthesia using two different ventilation techniques in obese patients.
Phase 4
- Conditions
- Health Condition 1: O- Medical and SurgicalHealth Condition 2: J958- Other intraoperative and postprocedural complications and disorders of respiratory system, not elsewhere classified
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Obese patients having BMI between 30 to 49.9 kg/m2
ASA physical status II and III
Age between 18 to 65 years of either sex
Adequate fasting status (6h for solids and 2h for clear liquids)
Exclusion Criteria
Patients having comet tail appearance prior to induction (baseline)
Failure to obtain clear ultrasonographic images
Drugs affecting the dynamics of gastrointestinal system
History of esophageal or gastrointestinal trauma or surgery
Failed facemask ventilation in either group (An experienced anaesthetist fails to maintain SpO2 of above 90% using 100% O2 with bag and mask ventilation with two hand techniques and use of oral airway)
More than one attempt at endotracheal intubation
Esophageal intubation
Occurrence of gastric content regurgitation or aspiration
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umber of patients who develop a new ‘comet tail sign’ suggestive of gastric insufflation after induction compared to preinductionTimepoint: At 0 and 10 minutes
- Secondary Outcome Measures
Name Time Method Change in arterial partial pressure of oxygen (PaO2), carbon dioxide (PaCO2), pH value and bicarbonate (HCO3-) at T1, T2 and T3 time intervalsTimepoint: At 0, 2 and 5 minutes;Change in cross sectional area (CSA) of gastric antrum (measured using gastric ultrasound) and gastric volume (calculated using Bouvet equation) after induction compared to preinductionTimepoint: At 0 and 10 minutes;Postoperative symptoms suggestive of gastric distention (bloating, burping, flatulence) and Post-operative Nausea and Vomiting (PONV)Timepoint: At 0 and 1 hour