Comparison Of The Outcome Of Treatment of Microneedling With Autologous Platelet- Rich -Plasma Versus Microneedling With Topical Insulin In The Treatment Of Post Acne Atrophic Scars.
Overview
- Phase
- Phase 2
- Status
- Completed
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Efficacy of Topical Insulin R with microneedling versus Platelets rich plasma in atrophic acne scars
Overview
Brief Summary
Microneedling with topical INSULIN is a simple, effective tool for building body's new collagen layers and thus an alternative to all erosive techniques such as lasers, peels. The skin responds to fine punctures with the release of growth factors. 8 It is a safe procedure that can be performed in the office without complications, with a good cost-benefit because it is economically viable without any effect on patient's daily activities. 9
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 20 Years to 50 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •postacne atrophic scars ≥ 2 on Goodman and Baron's acne scar-grading system
- •Either gender.
- •Age 20-50 years.
Exclusion Criteria
- •lactation and pregnancy
- •skin cancers and infection
- •photosensitivity like SLE ,XP
- •use of RETINOIDS in last 6 months.
Arms & Interventions
GROUP A Microneedling with PRP(platelete rich plasma)
Intervention: PRP( platelet rich plasma) and Insulin human (Drug)
GROUP B Microneedling with topical INSULIN
Intervention: PRP( platelet rich plasma) and Insulin human (Drug)
Outcomes
Primary Outcomes
Efficacy of Topical Insulin R with microneedling versus Platelets rich plasma in atrophic acne scars
Time Frame: Efficacy will be assesed upto 4 months.
Efficacy will be assessed by using Goodman and Baron Qualitative Scar Grading System
Secondary Outcomes
No secondary outcomes reported
Investigators
Nazia Jabeen
Principal Investigator
Jinnah Postgraduate Medical Centre