Prospective Evaluation of Esophageal Pathology Treatment of Head and Neck Carcinoma
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Stage I Adenoid Cystic Carcinoma of the Oral Cavity
- Sponsor
- Wake Forest University Health Sciences
- Enrollment
- 6
- Locations
- 1
- Primary Endpoint
- Abnormal endoscopic esophageal examination
- Status
- Terminated
- Last Updated
- 7 years ago
Overview
Brief Summary
Brief Summary:
RATIONALE: Comparing results of diagnostic procedures, such as esophagoscopy, done before and after radiation therapy and/or chemotherapy may help doctors predict a patient's response to treatment and help plan the best treatment.
PURPOSE: This clinical trial is studying esophagoscopy in evaluating treatment in patients with stage I-IV head and neck cancer who are undergoing radiation therapy and/or chemotherapy.
Detailed Description
OBJECTIVES: I. To assess the prevalence of esophageal pathology (any esophageal abnormality, specifically: esophagitis, stricture/web, infections, neoplasms) as identified by esophagoscopy in patients with HNCA before and 3 months following primary radiation and/or chemotherapy. II. To assess the changes in self-reported dysphagia symptoms as measured by the Eating Assessment Tool. OUTLINE: Patients undergo transnasal esophagoscopy at baseline and 3 months following completion of radiation therapy and/or chemotherapy.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Abnormal endoscopic esophageal examination
Time Frame: 3 months following completion of radiation therapy
Abnormal endoscopic esophageal examination, as defined by presence of: stricture, web, ring, erosive esophagitis, fungal esophagitis, viral esophagitis, Barrett's metaplasia, neoplasm, or other.
Secondary Outcomes
- Severity of self-rated swallowing dysfunction(3 months following completion of radiation therapy)