Effect of intravenus fibrinogen on blood transfusion in patients with acute gastrointestinal bleeding

Phase 3

Recruiting

• Conditions: Acute haemorrhagic gastritis.; Acute gastritis with bleeding; K29.01

• Registration Number: IRCT20140528017891N6
• Lead Sponsor: Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 25 March 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Having acute gastrointestinal bleeding
At least 18 years old

Exclusion Criteria

Congenital diseases or acquired coagulation disorder
Myocardial infarction two months ago
History of gastrointestinal bleeding
History of heart disease
Fibrinogen sensitivity
Pregnancy
Cirrhosis
Vasculitis
The presence of any type of cancer

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Rebleeding. Timepoint: 24 and 72 hours and 28 days after intervention. Method of measurement: Hemoglobin test.;The need for blood transfusion or its products. Timepoint: 24 and 72 hours and 28 days after intervention. Method of measurement: Hemoglobin test.

Secondary Outcome Measures

Name	Time	Method
Mortality. Timepoint: 24 and 72 hours and 28 days after intervention. Method of measurement: Observation and clinical examinations of the patient.;Administration in intensive care unit. Timepoint: 24 and 72 hours and 28 days after intervention. Method of measurement: Administrated patients in the intensive care unit.;Need for endoscopy. Timepoint: 24 and 72 hours and 28 days after intervention. Method of measurement: Endoscopy performed in patients under study.