Efficacy of Topical Liposomal Glucantime or Paromomycin in Combination With Systemic Glucantime for the Treatment of AC
- Conditions
- Protozoal diseases.Cutaneous Leishmaniasis
- Registration Number
- IRCT138809051475N4
- Lead Sponsor
- Mashhad University of Medical sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
1.Male or female aged between 12 to 60 years.
2.Parasitologically proven CL due to L. tropica.
3.History of failure to at least one full course of systemic Glucantime.
4.In general good health based on history and physical examination.
5.Number of lesion at most 4.
6.Lesion size less than 3 cm.
7.Signed informed consent voluntarily and knowingly**.
** Guardian’s signature for volunteer less than 18 years old.
Exclusion criteria:
1.Pregnant or lactating women and those who are planning to be pregnant in next 60 days.
2.Use of other types of treatment for CL.
3.Involvement in any other drug or vaccine trial during the study period.
4.Known heart, kidney, liver diseases based on history and physical exam.
5.Abnormal ECG
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Complete cure equal to Complete Re-epithelization of all lesions. Timepoint: weekly. Method of measurement: Taking digital pictures.
- Secondary Outcome Measures
Name Time Method