Evaluation of solid lipid nanoparticles containing Isotretinoin in treatment of acne
Phase 2
- Conditions
- Acne Vulgaris.Acne
- Registration Number
- IRCT201203283862N9
- Lead Sponsor
- ano Technology Research Center,Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Acne vulgaris patients with grade 2 and 3 base on Investigator Global Assessment; No receiving topical treatment of acne from 4 weeks before this regimen.
exclusion criteria:Androgenic acne;Acne due to drugs or cosmetics; Adrenal or Hormonal disorders.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Inflammatory and non-inflamatory lesions. Timepoint: Biweekly after starting treatment. Method of measurement: Observation and calculating of elementary lesions based on photographic image.
- Secondary Outcome Measures
Name Time Method Evaluation of side effects like skin irritation , erythema , skin dryness.pruritus. Timepoint: Biweekly. Method of measurement: Observation and severity scoring from + to +++.