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A randomized double-blinded clinical trial to investigate the role of ultrasound-guided transversus abdominis plane block

Phase 1
Conditions
Cancer
Surgery
Anaesthesia
Registration Number
PACTR202303539794048
Lead Sponsor
Bahir Dar University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Other
Sex
Female
Target Recruitment
60
Inclusion Criteria

All adults aged greater than 18 years old with the following criteria will be considered.
•Patients with the classification of ASA physical status II and III
•Patients who can tolerate a general anesthetic
• Patients undergoing cervical cancer surgery (radical hysterectomy) under general anesthesia,
•Patients who can provide informed consent for the surgery
•20 ml of 0.25 % bupivacaine will be given for cases (TAP block) at the end of the surgery
•Patients' weights are between 40-80 kg.
•Patients who can provide informed consent for the surgery

Exclusion Criteria

•Patients who have bleeding disorders
•Patients who are GCS <15
•Communication failure
•Patients who have an allergy to local anesthetics
•Patients who have multiple site surgery (outside of abdomen)
•Patients who have underlying cardiovascular diseases
•Patients with chronic pain and opioid use (using oral morphine greater than 100 mg daily).

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The primary endpoint is postoperative pain which a numerical rating scale will assess
Secondary Outcome Measures
NameTimeMethod
Total postoperative analgesic consumption: the total amount of analgesic requirement within the given postoperative period <br>Time for first-time analgesic request: the initial time in which the patient feels pain and asks for analgesia<br> Complications: any adverse events reported after surgery
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