Validation test (ReceptIVFity-test”) to predict the chance of pregnancy with IVF or IVF-ICSI treatment based on bacteria compositio

Not Applicable

Completed

• Conditions: In vitro fertilisation (IVF) and intracytoplasmic sperm injection (IVF-ICSI); Pregnancy and Childbirth

• Registration Number: ISRCTN83157250
• Lead Sponsor: Erasmus University Medical Centre

Brief Summary

2019 Results article in https://pubmed.ncbi.nlm.nih.gov/31119299/ results (added 17/07/2020) 2018 Protocol article in https://pubmed.ncbi.nlm.nih.gov/30526664/ (added 06/09/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-08-30
• Study Completion: 2018-12-01
• Last Update Posted: 18 September 2023

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 192

Inclusion Criteria

1. Female
2. Indication for an IVF or IVF-ICSI procedure
3. Aged 20-44 years
4. Willing to provide a urine sample and a vaginal swab
5. Willing to provide informed consent
6. Male partner

Exclusion Criteria

1. No transferable embryos after IVF or IVF-ICSI
2. Indication for emergency IVF because of cancer or other reasons
3. AFS (American Fertility Society) III/IV classified endometriosis and pre-treatment with a GnRH (gonadotropin-releasing hormone) analogue
4. >3 weeks use of hormonal contraceptives 3 months prior to start IVF or IVF-ICSI
5. Pregnant previously to the start of the IVF or IVF-ICSI (including miscarriage)
6. Hormonal treatments 3 months prior to start IVF or IVF-ICSI
7. Use of sperm donation

Study & Design

• Study Type: Observational
• Study Design: Not specified