Risk of Ectopic Pregnancy and Variation of Luteal Estradiol and Progesterone Levels in IVF
- Conditions
- Ectopic Pregnancy
- Registration Number
- NCT02793089
- Lead Sponsor
- IVI Vigo
- Brief Summary
This study evaluates the increased risk of ectopic pregnancy associated with marked variation of estradiol during the early luteal phase and high progesterone on hCG day in IVF.
- Detailed Description
This is a retrospective cohort study of 578 patients who had no risk of EP (672 fresh transfer IVF cycles) between January 2005 and December 2014. Few studies have reported the relation between hormonal levels and ectopic pregnancy (EP) in IVF. Investigators describe EP incidence according to estradiol (E2) and progesterone (P4) levels on hCG day and seven days later (hCG+7) or their variation between both days.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 578
- Normal Fallopian tubes in HSG and /or laparoscopy
- Normal Uterus: Abscence of myomas and Müllerian anomalies .
- Previous Ectopic Pregnancy .
- Recurrent Abortion .
- Tubal Factor : pelvic inflammatory disease, Hydrosalpinx
- Previous abdominal surgery (except laparoscopy) .
- Prior Peritonitis
- Smoking (at least 1 cigarette/day) .
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Ectopic pregnancy rate Up to 108 months
- Secondary Outcome Measures
Name Time Method
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