Evaluation of Transpharyngeal Doppler Sonography as a Cerebral Monitoring Tool in Cardiac Surgery
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 30
- Locations
- 2
- Primary Endpoint
- Accuracy of cerebral flow velocity measurement
Study Overview
Brief Summary
This prospective interventional study investigates transpharyngeal sonography (TPS) as an additional neuromonitoring strategy to assess cerebral perfusion during cardiovascular surgery. In the first part of the study the investigators will investigate the feasibility of TPS for visualization of aortic arch branches including the innominate and the carotid arteries in patients undergoing cardiac surgery with cardiopulmonary bypass. In the second part the investigators plan to adopt the investigators previous experiences on TPS to a selected population of patients undergoing ascending aortic and/or arch repair in hypothermic circulatory arrest (HCA).
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Sequential
- Primary Purpose
- Diagnostic
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Cardiovascular Surgery
- •Age > 18 yrs
- •Informed Consent
Exclusion Criteria
- •Contraindication for TPS
- •Carotid artery stenosis
Arms & Interventions
20 patients (1-20) validation arm
Accuracy of cerebral flow measurement between TPS and CDS in 20 patients undergoing cardiovascular surgery with cardiopulmonary bypass
Intervention: Transpharyngeal Doppler sonography (TPS) (Diagnostic Test)
20 patients (1-20) validation arm
Accuracy of cerebral flow measurement between TPS and CDS in 20 patients undergoing cardiovascular surgery with cardiopulmonary bypass
Intervention: Conventional colour-coded Duplex sonography (CDS) (Diagnostic Test)
20 patients (21-40) HCA arm
Assessment and comparison of TPS and CDS in hypothermic circulatory arrest (HCA) during cardiovascular surgery
Intervention: Transpharyngeal Doppler sonography (TPS) (Diagnostic Test)
20 patients (21-40) HCA arm
Assessment and comparison of TPS and CDS in hypothermic circulatory arrest (HCA) during cardiovascular surgery
Intervention: Conventional colour-coded Duplex sonography (CDS) (Diagnostic Test)
Outcomes
Primary Outcomes
Accuracy of cerebral flow velocity measurement
Time Frame: intraoperative phase, expected to be ca. 4 hours
Cerebral blood flow velocity measurements will be performed with transpharyngeal Doppler sonography (TPS) and conventional colour-coded Duplex sonography (CDS). Doppler flow velocities (obtained at the same intraoperative phase and at the same time) will be compared between TPS and CDS TPS and different Doppler techniques.
Secondary Outcomes
- Hypothermic Circulatory Arrest(intraoperative phase, expected to be ca. 4 hours)