Ivabradine in controlling elevated heart rate among sick patients
Phase 3
Completed
- Conditions
- Health Condition 1: null- Sinus Tachycardia
- Registration Number
- CTRI/2010/091/002969
- Lead Sponsor
- Fluid Research Grant Christian Medical CollegeVellore Tamilnadu
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
a)Aged above 18 years
b)Sinus rhythm with heart rate above 120 bpm
c) 24 hours of admission to the ICU with a diagnosis of shock.
d)In case of patients admitted with Organophosphorus poisoning, they should have been off atropine for at least 48 hours.
Exclusion Criteria
ICU Physician assessment
Sick sinus syndrome
Sinu-atrial block
Pacemaker-dependency
3rd degree AV block
Ongoing fluid/volume loss
On concomitant use of potent CYP3A4 inhibitors:
Azole antifungals (ketoconazole, itraconazole),
Clarithromycin , erythromycin, josamycin, telithromycin,
HIV protease inhibitors (nelfinavir, ritonavir)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method