Psychobiological Assessment and Enhancement of Team Cohesion and Psychological Resilience Using a Virtual Team Cohesion Test.
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 486
- 试验地点
- 1
- 主要终点
- Change in score on computer game task
研究概览
简要总结
This study attempts to identify the psychological, behavioral, physiological, and hormonal predictors and mechanisms of an individual's ability to develop cohesion in a group working together as a team; and examine if administration of the prosocial neuropeptide oxytocin enhances the development of team cohesion. Through a deeper understanding of the underlying psychobiological predictors and mechanisms of team cohesion, the prospective identification of individuals whose unique characteristics promote or inhibit the development of group cohesion will become possible.
详细描述
The investigators will study up to one thousand subjects who will be randomized into same-gendered teams of three or volunteer as acquainted groups of three . Teams will be randomized to receive oxytocin or placebo. The investigators will first measure baseline personality traits including prosocial orientation. Cohesion will then be measured using a cooperative, virtual unmanned aerial vehicle (UAV) flying mission. All online behavior will be recorded within the task and all offline, real world, behavior will be video recorded throughout the study by digital cameras for later behavioral coding. To measure biobehavioral synchrony, autonomic physiology will be recorded and saliva samples will be taken throughout behavioral testing.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 28 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 18-28
- •Speak English
- •Ability to use a nasal spray
排除标准
- •Positive urine pregnancy test
- •History of psychiatric or neurologic disorder
- •Use of illicit drugs in the past month
- •History of moderate-severe alcohol use disorder as defined by DSM-V criteria
- •Sensitivity to preservatives (in particular E 216, E 218 and chlorobutanol hemihydrate)
- •Nasal obstruction, discharge, or bleeding
- •Habitually drinks large volumes of water
- •Taking testosterone, estrogen/progesterone supplement, or serotonin-1a receptor agonists/antagonists
- •Currently meets Diagnostic and Statistical Manual-5 (DSM-V) criteria for severe major depressive disorder with suicidal thoughts or actions
研究组 & 干预措施
Treatment
Treatment group will receive either 20IU or 40IU intranasal oxytocin
干预措施: Oxytocin (Drug)
Placebo
Placebo group will receive a saline nasal spray
干预措施: Placebo comparator (Other)
结局指标
主要结局
Change in score on computer game task
时间窗: Baseline, 2 hours after drug/placebo administration
Subjects will work together in groups of 2-4 performing a computer-based task flying a virtual plane.
次要结局
- Change is psychophysiological output(Time based variability analyzed for 5 minute or 20 minute events)
研究者
Joshua Woolley
Principal Investigator
University of California, San Francisco