acetylcysteine as a Preventive Measure for Contrast Induced Nephropathy in Intensive Care Patients with Renal Insufficiency.
- Conditions
- Renal insufficiency (not yet requiring renal replacement therapy)
- Registration Number
- NL-OMON20378
- Lead Sponsor
- one
- Brief Summary
Will be written after completion of study and anlysis of results
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 246
Inclusion Criteria
1. (Chronic or acute) renal insufficiency (not presently on renal replacement therapy) defined as a plasma creatinine > 180 ìmol/L;
2. Planned diagnostic imaging procedure requiring the use of intravenous radiographic contrast agents;
Exclusion Criteria
1. Pregnancy;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Rise in plasma creatinine > 25% within 48 hours after contrast administration.<br /><br>Need for CVVH therapy at any moment during stay in ICU;<br /><br>2. Duration of CVVH therapy, if initiated;<br><br />3. Renal insufficiency (for which ongoing renal replacement therapy) at ICU-discharge .
- Secondary Outcome Measures
Name Time Method