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临床试验/NCT07469618
NCT07469618尚未招募不适用

Efficacy of Cognitive Stimulation Therapy Integrated With Stress Reduction Intervention for Adults With Mild Cognitive Impairment

University of the Punjab0 个研究点目标入组 12 人开始时间: 2026年3月1日最近更新:
干预措施

试验速览

阶段
不适用
状态
尚未招募
入组人数
12
主要终点
Change in Montreal Cognitive Assessment (MoCA) total score from baseline to 7 weeks

研究概览

简要总结

The aim of this study is to determine if integrating a culturally congruent indigenous stress reduction intervention into Cognitive Stimulation Therapy (CST) enhances cognitive outcomes in Pakistani adults with Mild Cognitive Impairment (MCI).

详细描述

Mild Cognitive Impairment (MCI) is characterized by noticeable decline in cognitive functioning that is greater than expected for normal aging but does not significantly interfere with daily functioning. Cognitive Stimulation Therapy (CST) has been shown to improve cognitive functioning through structured activities that stimulate memory, attention, and problem-solving abilities. However, psychological stress is an important factor that may contribute to cognitive decline and reduced engagement in cognitive activities. The present randomized controlled trial aims to evaluate whether integrating a culturally congruent indigenous stress reduction intervention with CST enhances cognitive outcomes and reduces perceived stress among Pakistani adults with MCI. Participants will be randomly assigned to one of three groups: (1) CST integrated with a CBT-based stress reduction intervention, (2) CST only, and (3) a no-intervention control group. The interventions will be delivered over a period of seven weeks. Cognitive functioning will be assessed using the Montreal Cognitive Assessment (MoCA), and perceived stress will be assessed using the Perceived Stress Scale (PSS). Assessments will be conducted at baseline and after completion of the intervention period. The study aims to determine whether the integrated intervention provides greater benefits in improving cognitive functioning as compared to CST alone.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
45 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adults aged 45 years and above
  • Individuals with education up to Matric
  • Individuals who obtain a score lower than 23 on Montreal Cognitive Assessment (MoCA) suggesting the presence of cognitive decline.
  • Individuals who obtain a score of 14 or more on the Perceived Stress Scale suggesting increased levels of perceived stress (moderate and high)
  • Individuals who obtain score ranged from 13 to 25 (Poor to Adequate) on Quality of Life in Alzheimer's Disease (Qol-AD)

排除标准

  • Diagnosis of dementia or major neurocognitive disorder
  • Presence of severe psychiatric illness (e.g., psychosis, major depressive episode)
  • Significant hearing or visual impairments that interfere with participation
  • Currently undergoing psychological or cognitive therapy
  • Any neurological condition that may interfere with cognitive assessment (e.g., stroke, Parkinson's disease)

研究组 & 干预措施

Cognitive Stimulation Therapy integrated with Stress Reduction Intervention

Experimental

Participants receive Cognitive Stimulation Therapy integrated with Stress Reduction Intervention for 7 weeks.

干预措施: Cognitive Stimulation Therapy integrated with Stress Reduction Intervention (Behavioral)

Cognitive Stimulation Therapy (CST)

Active Comparator

Participants receive Cognitive Stimulation Therapy sessions for 7 weeks.

干预措施: Cognitive Stimulation Therapy (Behavioral)

Control Group

No Intervention

Participants will not receive any structured therapy during the 7 week study period.

结局指标

主要结局

Change in Montreal Cognitive Assessment (MoCA) total score from baseline to 7 weeks

时间窗: 7 weeks

The Montreal Cognitive Assessment (MoCA) will be used to assess overall cognitive functioning, including attention, memory, language, executive functions, and visuospatial abilities. The MoCA total score ranges from 0 to 30, with higher scores indicating better cognitive functioning. Assessments will be conducted at baseline and after completion of the 7-week intervention period.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Saliha Moazzam

Student

University of the Punjab

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