MedPath

The Role of Thyroid Function in the Development and Prognosis of Stanford Type A Aortic Dissection.

Conditions
Stanford Type A Aortic Dissection
Registration Number
NCT03146494
Lead Sponsor
Beijing Anzhen Hospital
Brief Summary

A total of 300 consecutive cardiac patients will receive preoperative thyroid function profile evaluation, including 150 patients with Standford type A aortic dissection (STAAD) and 150 normal human.For one thing, we will compare the two groups and study the role of thyroid function in the develoment of STAAD. For another, we will collect all the perioperative data of the STAAD group and study the role of thyroid function in the prognosis of STAAD.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
300
Inclusion Criteria

Adult patients with STAAD will underwent aortic surgery who are willing and able to give informed consent for participation in the study.

Exclusion Criteria

The main initial exclusion criteria included clinical evidence of sepsis or cachexia or concomitant presence of any predominant severe systemic disease.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The Role of Thyroid Function in the Development of STAAD.30 days

Patients were followed for 30-day mortality and major adverse events (MAEs) as defined by the need for rethoracotomy, occurrence of postoperative heart failure, neurologic deficit, lung failure, renal failure, or sepsis.

The Role of Thyroid Function in the Prognosis of STAAD.30 days

Patients were followed for 30-day mortality and major adverse events (MAEs) as defined by the need for rethoracotomy, occurrence of postoperative heart failure, neurologic deficit, lung failure, renal failure, or sepsis.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Wenjian Jiang

🇨🇳

Beijing, Beijing, China

© Copyright 2025. All Rights Reserved by MedPath