Investigation of the Effect of Different Blood Groups on the Survival of Intensive Care Patients

Intensive care units; They are units where advanced technological tools and equipment are used to provide the highest level of benefit to life-threatened patients, and physicians and nurses specializing in the treatment and care of patients are involved. Intensive care patients; '' To prevent patients who are at risk due to physiological decompensation and patients who are physically physiologically fluctuating, need a treatment to be carried out with the harmony between physician and nurse to ensure survival, the application of this treatment without showing waves, especially details and care, and unexpected adverse events. and patients who require continuous monitoring to provide immediate intervention by the intensive care team. Intensive care patients, as can be understood from the definition, are the patients whose general conditions change rapidly due to the presence of a life-threatening condition, due to the impact of several systems that require close monitoring and control vital functions.

Respiratory, cardiovascular, neurological, etc. Many conditions, such as chronic diseases, genetic, individual and environmental factors, of patients who are in danger of life due to many important health problems can affect the prognosis of the patients. In addition to these factors, although there is insufficient evidence, blood groups are reported to be effective in the survival of intensive care patients. Whatever the underlying situation is, the most important thing is undoubtedly the blood for the maintenance of a healthy life. It is known to affect human health in many cases, from the amount of blood circulating in the vein to the structure of blood cells.

It was found for the first time in the years of 1899 and 1900 that human blood differs from individual to individual due to some physiological features. These different blood groups discovered are A, B and AB. Later, with the discovery of the Rh factor along with the O (zero) blood group, studies on the effects and differences of blood groups on humans have increased rapidly. Today, studies on the relationship between blood groups and diseases are ongoing.

As a result of some studies; It has been determined that the AB blood group plays a role as a risk factor in both venous thromboembolism and coronary artery disease. The risk of both arterial and venous thrombotic events in the AB blood group There is evidence that it has high levels of vonWillebrand factor (vWF) and factor VIII. Depending on the limitation of mobilization in intensive care patients, it may increase the negative effect of the blood group on the patient compared to the patients hospitalized in other clinics. However, in patient groups with a high risk of bleeding, this may provide additional benefit for patients with AB blood group with higher levels of vonWillebrand factor (vWF) and factor VIII. In their research, Franchini et al. Reported that bleeding rate increased significantly in patients with O blood group, especially in surgical procedures with high risk of blood loss. Therefore, it has been observed that patients with AB blood group are more likely to survive after major heart surgery and this situation is explained in relation to the decrease in the number of blood transfusions. The results of metaanalysis study of Dentali et al. Also pointed out that having an O blood group in terms of bleeding may be an important genetic factor. It is important that the intensive care nurse includes this information in patient care.

In a study conducted to determine the link between ABO blood group, lipid profiles and coronary artery disease and to determine the effect size of the link, patients in the A blood group were found to have higher total cholesterol rates while lower LDL rates. Jiang et al; They found that ABO blood groups were not associated with age, gender, and blood pressure in stable coronary artery patients undergoing percutaneous coronary intervention, but blood groups were associated with 2-year cardiac death.