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临床试验/NCT03644901
NCT03644901已完成不适用

Investigating the Role of ABO Blood Group in the Response to the Nonsurgical Periodontal Treatment.

Damascus University1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2018年1月15日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
60
试验地点
1
主要终点
Change in relative attachment level.

研究概览

简要总结

The aim of this study is to find out if one blood group phenotype is more responsive than the others to the nonsurgical periodontal treatment.

详细描述

To the best of our knowledge, this is the first (research) randomized clinical trial that assesses how patient respond to the nonsurgical periodontal treatment based on their blood group phenotype.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
20 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • systematically healthy.
  • have at least 20 teeth excluding the third molars.
  • had not received any periodontal treatment or antibiotic therapy for dental or medical reason 6 month prior to the study.
  • diagnosed with generalized chronic periodontitis (>30% of the sites have probing depth ≥4), and a minimum of six teeth with probing depth of 5-6 mm.

排除标准

  • smokers and alcoholics.
  • pregnancy.
  • history of a systematic disease such as diabetes, leukemia, epilepsy.
  • participants who are unable to perform routine oral hygiene.
  • use of orthodontic appliances.
  • participants who are unable to perform routine oral hygiene.

结局指标

主要结局

Change in relative attachment level.

时间窗: measures will be taken at baseline and after two months from treatment.

the relative attachment level measures the length form the base of the periodontal pocket to a stent

次要结局

  • Change in plaque Index(index will be taken at baseline and after two months from treatment.)
  • Change in periodontal probing depth.(measures will be taken at baseline and after two months from treatment.)
  • Change in gingival index(index will be taken at baseline and after two months from treatment.)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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