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临床试验/NCT03947801
NCT03947801已完成不适用

Dairy Consumption During a High-intensity, High-volume Training Week in Young Athletes

Brock University1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2019年7月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
30
试验地点
1
主要终点
Height (cm)

研究概览

简要总结

Our proposed study is a 5-d double-blind randomised cross-over trial, seeking to simulate a training identification camp in competitive adolescent soccer players

The purpose of the proposed study is to investigate whether increased protein consumption by Greek yogurt, compared to an isoenergetic carbohydrate (CHO) control supplement, consumed immediately following exercise training, prior to sleep and between breakfast and lunch, for a week during an intense training period (high volume, high intensity) will:

  • Attenuate the pro-inflammatory response (cytokines, acute phase proteins)
  • Reduced the severity of muscle damage and impairment (creatine kinase)
  • Maintain performance

Secondary outcome measures:

- Increase bone turnover (in favour of formation)

详细描述

The proposed study is a randomized, double-blinded, cross-over trial. The protocol will consist of an information session, two identical training camps consisting of 5 consecutive days of intensified soccer training, differing only by nutritional intervention, and identical pre-and post-training session testing. Each testing block will be separated by 28-d to allow for an adequate wash-out and recovery period, during which participants would resume their regular soccer activities

Study Procedures:

All tests and measurements will be performed within eight-weeks. Specifically, participants will attend 1 information session, two identical pre- and post- training/testing sessions and two identical soccer specific training camps.

Information session:

One week prior to the initial soccer specific training camp, participants will be informed of all tests and procedures that will take place and be familiarized with all testing protocols.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Other
盲法
Double (Participant, Investigator)

入排标准

年龄范围
11 Years 至 16 Years(Child)
性别
All
接受健康志愿者
是

入选标准

  • •Participant are female within the desired age ranges (11-16y)
  • •Participants are competitive soccer players
  • •Previous participation in high-performance training environment (periodization)

排除标准

  • •Participant is not female or falls outside of the desired age ranges (11-16y)
  • •Chronic/frequent use of medications that could affect inflammatory function - NSAIDS or Corticosteroids.
  • •Musculoskeletal injury - resulting in the inability to train and/or perform the baseline/post testing.

研究组 & 干预措施

Greek Yogurt condition

Experimental

3x 160g of 0% Plain Greek yogurt (~115 kcals, 17 g protein, ~11.5 g carbs, 0 fat) consumed immediately following the training session, 1 h prior to bedtime, as well as one serving between breakfast and lunch on the subsequent day.

干预措施: Greek Yogurt (Other)

Isoenergetic condition - Carbohydrate

Placebo Comparator

3x 30g of isoenergetic CHO supplement (~115 kcal, 0.04 g protein, ~28.6 g carbs, 0 fat) consumed immediately following the training session, 1 h prior to bedtime, as well as one serving between breakfast and lunch on the subsequent day.

干预措施: Isoenergetic carbohydrate (Other)

结局指标

主要结局

Height (cm)

时间窗: 8 weeks

Anthropometric measures

Body fat (%)

时间窗: 8 weeks

Body composition

Serum concentrations of OPG (pg/ml)

时间窗: 8 weeks

Bone formation marker

Serum concentrations of TRAP (ng/ml)

时间窗: 8 weeks

Bone resorption marker

Serum concentrations of CTX (ng/ml)

时间窗: 8 weeks

Bone resorption marker

Body mass (kg)

时间窗: 8 weeks

Anthropometric measures

Serum concentrations of BAP (ng/ml)

时间窗: 8 weeks

Bone formation marker

Serum concentrations of PINP (ng/ml)

时间窗: 8 weeks

Bone formation marker

Serum concentrations of RANKL (pg/ml)

时间窗: 8 weeks

Bone resorption marker

Plasma concentrations of IL-6 (pg/ml)

时间窗: 8 weeks

Plasma concentrations of pro-and-anti-inflammatory cytokines

Plasma concentration of creatine kinase (U/L)

时间窗: 8 weeks

Muscle damage

Seated height (cm)

时间窗: 8 weeks

Used to calculate maturity offset in years from peak height velocity

Rate of perceived exertion

时间窗: 8 weeks

1-10 scale of perceived exertion

Plasma concentrations of TNF-alpha (pg/ml)

时间窗: 8 weeks

Plasma concentrations of pro-and-anti-inflammatory cytokines

Plasma concentrations of irisin (ng/ml)

时间窗: 8 weeks

Plasma concentrations of pro-and-anti-inflammatory cytokines

Plasma concentrations of IL-10 (pg/ml)

时间窗: 8 weeks

Plasma concentrations of pro-and-anti-inflammatory cytokines

Plasma concentrations of CRP (pg/ml)

时间窗: 8 weeks

Plasma concentrations of pro-and-anti-inflammatory cytokines

次要结局

  • Serum concentration of IGF-1 (pg/ml)(8 weeks)
  • Plasma concentration of TBARS(8 weeks)
  • Saliva concentrations of cortisol (ug/dl)(8 weeks)
  • Saliva concentrations of testosterone (pg/ml)(8 weeks)
  • Plasma concentration of ROS(8 weeks)
  • Oxidative stress(8 weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

PKlentrou

Professor and Associate Dean

Brock University

研究点 (1)

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