Effect of electroacupuncture for treating constipation and gut microbiota in Parksion's diaease: a randomized clinical trial

Phase 1

Recruiting

• Conditions: Parkinson's disease

• Registration Number: ITMCTR2000004052
• Lead Sponsor: inyi People's Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. In line with the diagnostic criteria of Western medicine for Parkinson's disease;
2. Meet the diagnostic criteria of Roman IV diagnostic criteria for functional constipation;
3. Aged between 40 to 80 years old;
4. Hoehn & Yahr grade < 3;
5. Informed consent and willing to participate in the study.

Exclusion Criteria

1. Patients with constipation due to serious gastrointestinal and digestive diseases;
2. Patients with severe mental illness or cognitive impairment (Mini-mental State Examination(MMSE): the illiterate; educational level is < 17 scores, the primary school educational level is < 20 scores, and the secondary school and above educational level is< 24 scores);
3. Patients with serious cardiovascular and cerebrovascular diseases, hematopoietic diseases, malignant tumors and other serious life-threatening diseases;
4. Patients who used probiotics or antibiotics within 1 month before sample collection.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Composition of gut microbiota;spontaneous bowel movements (SBMs) per week;

Secondary Outcome Measures

Name	Time	Method
Bristol;CCS;UPDRS-III;PDQ-39;HAMD;HAMA;