Monochloroacetic acid versus cryotherapy in the treatment of warts: A Randomised Clinical Trial (WARTS-2) - WARTS-2

Conditions: All patients from the age of 4 onward, who present themselves to their practice with one or more new warts of the type vulgaris on hands or feet.
MedDRA version: 9.1Level: LLTClassification code 10010115Term: Common warts
MedDRA version: 9.1Level: LLTClassification code 10035158Term: Plantar warts

Registration Number: EUCTR2009-012210-48-NL

Lead Sponsor: eiden University Medical Centre

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Authorised-recruitment may be ongoing or finished

Sex: All

Target Recruitment: Not specified

Inclusion Criteria

All patients from the age of 4 onward, who present themselves to their practice with one or more new warts of the type vulgaris on hands or feet will be included.
New warts are warts which are presented for the first time in general practice by patients who have had no general practice (or dermatological) treatment for warts in the past year.
Are the trial subjects under 18? yes
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Immuno-compromised patients
Patients with mosaic warts larger than 1 cm in diameter
Patients with warts who are pregnant or who are breastfeeding.

Study & Design

Study Type: Interventional clinical trial of medicinal product

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary end point(s): ‘Cure', meaning all hand- or plantar wart(s) have totally disappeared (normal skin) at 13 weeks.;Main Objective: Is treatment with monochloroacetic acid more effective than treatment with cryotherapy regarding patients with handwarts?<br><br>Is treatment with monochloroacetic acid more effective than combination therapy (treatment with first salicylic acid followed by cryotherapy) regarding patients with plantar warts?<br>;Secondary Objective: To examine the ideas of (parents of) patients having warts, including hindrance of warts, usage of over the counter therapy and expectations concerning over the counter therapy as well as treatment by their general practioner.

Secondary Outcome Measures