The Effect of Eccentric Exercise on Biomarkers of Exercise Induced Muscle Damage and Oxygen Uptake: Differences Between Phases of the Menstrual Cycle
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 1
- 主要终点
- Maximal isometric torque
研究概览
简要总结
The existing literature examining the effect of female sex hormones across the phases of the menstrual cycle on muscle microdamage and oxygen uptake is limited. The protective role of estrogens against muscle microdamage is supported by findings from some studies; however, it is questioned by others. The aim of the present study was to investigate the effect of eccentric exercise on biomarkers of muscle microdamage and on oxygen uptake during two phases of the menstrual cycle in healthy premenopausal women.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 28 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •No known medical history
- •Not receiving any medication or dietary supplementation.
- •Stable menstrual cycle
排除标准
- •Pathological conditions the last month before enrolment in the study
- •Low limb injury the past 4 months
- •Unstable menstrual cycle
研究组 & 干预措施
Eccentric exercise
A group of female subjects performed an exercise with one leg and an exercise with the other leg, separated by 2 weeks. Before and 2 days after the exercise sessions, performance was assessed.
干预措施: Isokinetic eccentric exercise using knee extensors of the right lower limb (Other)
Eccentric exercise
A group of female subjects performed an exercise with one leg and an exercise with the other leg, separated by 2 weeks. Before and 2 days after the exercise sessions, performance was assessed.
干预措施: Isokinetic eccentric exercise using knee extensors of the left lower limb (Other)
结局指标
主要结局
Maximal isometric torque
时间窗: From enrollment to the end of the intervention at 2 weeks
maximal performance during 5 sec isometric knee extensors contraction, assessed pre and 48 h post eccentric exercise
Delayed onset muscle soreness
时间窗: From enrollment to the end of intervention at 2 weeks
Palpation of the muscle belly, performed pre and 48h post eccentric exercise
Oxygen consumption
时间窗: From enrollment to the end of the intervention at 2 weeks
During the isokinetic eccentric exercise, participants were attached to a gas analyser for continuously measuring oxygen consumption.
Duration of the isokinetic exercise
时间窗: From enrollment to the end of intervention at 2 weeks
The total duration of exercise performed on the isokinetic dynamometer was recorded
次要结局
未报告次要终点
研究者
Vassilis Paschalis
Principal Investigator
National and Kapodistrian University of Athens