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Effect of Ayurvedic formulation in Pandu Roga (Anemia).

Phase 2
Not yet recruiting
Conditions
Iron deficiency anemia, unspecified. Ayurveda Condition: PANDUROGAH,
Registration Number
CTRI/2025/05/087787
Lead Sponsor
Abhilashi Ayurvedic College and Research Institute
Brief Summary

**A COMPARATIVE CLINICAL STUDY OF DRAKSHA GHRITA WITH FERROUS ASCORBATE IN PANDU ROGA W S R  TO IRON DEFICIENCY ANEMIA**



**Public title of the study**



Effect of Ayurvedic formulation in Pandu Roga  Anemia



**Scientific Title of the study**



A comparative Clinical Study of Draksha Ghrita with Ferrous Ascorbate in Pandu Roga W S R to Iron Deficiency Anemia



**Principal Investigator’s Name**



Dr  Richa Thakur



P G Scholar



**Institute**



Abhilashi Ayurvedic Medical College and Research Institute  Chail  Chowk



Mandi H P



**Guide**



Dr  Yogesh Sharma



M D    Ayu   Professor



**Co  Guide**



Dr  Pankaj Sharma



M D  Ayu   Associate Professor



**Place of Study**



Abhilashi Ayurvedic Medical College and Research   Institute  Chail Chowk



Mandi H P



**Introduction**



Rapid lifestyle changes are increasing nutritional disorders



Iron Deficiency Anemia  IDA  is a major global and Indian health issue



WHO  One third of global population is anemic



IDA causes fatigue  heart issues  low immunity  etc



Ayurveda identifies IDA as Pandu Roga  linked with Pitta dosha imbalance



**Side effects with Modern Medicine**



Common treatments use iron salts  Ferrous sulfate  ascorbate  etc



Side effects include nausea  constipation  metallic taste  etc



Need for safe  effective  natural alternatives



**Ayurvedic Perspective**



Pandu Roga described in Charak Samhita



Draksha Ghrita  A classical Ayurvedic formulation



Ghee based herbal compound



Benefits  Pacifies Pitta  strengthens digestion  promotes healthy blood  Rakta Dhatu



**Aim and Objectives**



Aim  Evaluate the efficacy of Draksha Ghrita in managing Pandu Roga  IDA



Objectives



1  Compare Draksha Ghrita with Ferrous Ascorbate



2  Assess safety of Draksha Ghrita



**Methodology**



Design  Randomized clinical trial



Subjects  30 patients with IDA  Hb 7 to 11 gm percent  aged 18 to 45 years



Groups



Group 1  Draksha Ghrita  5g twice day



Group 2  Ferrous Ascorbate  100 mg once day



Duration  60 days



Follow up  Day 20  40  60



**Inclusion Exclusion Criteria**



Inclusion



Age 18 to 45 years



Hb  7 to 11 gm percent



Willingness to participate



**Exclusion**



Major systemic illness    Tuberculosis  R A  Gastric Ulcers  Bleeding Disorders  Menstrual Disorders   CKD   Hypertension   Diabetes Mellitus   Malignancies



Hb greater than 7 or Less than 11 gm percent



Age greater than 18 or Less than 45



**Assessment Criteria**



Subjective



Panduta  Daurbalyata  Hridyaspandanam  Ayasaja Swasa  Bhrama  Pindikodwestana  Pallor  Weakness  Palpitations  Breathlessness  Dizziness  Calf pain



Objective



CBC  ESR  Peripheral smear  Serum Ferritin  RFT  LFT



**Outcome Grades**



Marked  Less than 75percent relief and Hb more than or equals  3 gm percent



Moderate  50to 75percent and Hb more than or equals 2 gm percent



Mild  25 to 50percent and Hb more than equals 1 gm percent



No Improvement  greater than 25percent and Hb  greater than 1 gm percent



**Trial Drug  Draksha Ghrita**



Composition



Go ghrita  Ghee   1 part



Draksha  Vitis vinifera   One half part  paste form



**Benefits**



Treats anemia  jaundice  digestive issues



Pacifies Pitta and Vata



Improves blood and nutrition assimilation

Detailed Description

Not available

Recruitment & Eligibility

Status
Not Yet Recruiting
Sex
All
Target Recruitment
30
Inclusion Criteria

Patient having Hb in between 7-11 gm percent Patient willing to participate in the trial.

Exclusion Criteria

Patient having age group less than 18yrs or more than 45 yrs Patient having Hb level less than 7gm percent and greater than 11gm percent Patient suffering from major systemic illness Tuberculosis,Rheumatoid arthritis, Gastric ulcers, bleeding disorders( Menstrual disorders) , CKD, Hypertension,Diabetes mellitus, Malignancies.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Assessment of effect of two therapies will be done on the basis of prepared performa and improvement in parameters . Subjective Criteria:60 days
Panduta - Twacha, nakha, netra, jihwa, hastapada60 days
Daurbalyata60 days
Hridyaspandanam60 days
Ayasaja swasa60 days
Bhrama60 days
Pindikodwestana60 days
Objective Criteria-60 days
CBC with ESR60 days
PBF( Peripheral blood film)60 days
RFT( Renal function test)60 days
LFT( Liver function test)60 days
S.Ferrintin60 days
Secondary Outcome Measures
NameTimeMethod
Improvement in criteria listed in different scales.Marked Improvement - 75% Relief in clinical features and rise in Hb 3gm%

Trial Locations

Locations (1)

Abhilashi Ayurvedic college and Research Institute Chailchowk Mandi H.P.

🇮🇳

Mandi, HIMACHAL PRADESH, India

Abhilashi Ayurvedic college and Research Institute Chailchowk Mandi H.P.
🇮🇳Mandi, HIMACHAL PRADESH, India
DrRicha Thakur
Principal investigator
9459359206
richa17thakur@gmail.com

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