Safety and efficacy of sacubitril/valsartan in patients with congenital heart diease with systemic right ventricular dysfunction – a prospective observational study
Not Applicable
- Conditions
- Health Condition 1: I508- Other heart failure
- Registration Number
- CTRI/2024/02/063203
- Lead Sponsor
- Pediatric Cardiac Society of India
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
After obtaining written informed consent, all consecutive patients with systemic right ventricular dysfunction,
ie, systemic right ventricular ejection fraction (sRV EF) =40% or fractional area change (FAC) =35%, assessed
by ECHO would be included.
Exclusion Criteria
1. Univentricular physiology
2. Systolic blood pressure < 90mmHg or <5th centile for age and height (whichever is lower)
3. GFR < 30ml/min/1.73m2
4. Serum potassium > 5.5 mEq/L
5. Previous intolerance to ACEi/ARB/ARNI
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method