Exploration of the Role of Vision on Spatial Cognition

Recruiting

• Conditions: Visual Deficiencies
• Interventions: Other: Mental imagery task; Other: Proprioceptive spatial representation tasks; Other: Tasks assessing number sense based on relative positions or lengths; Other: WISC V Similarity and Span Test; Other: WISC V Arithmetic subtest

• Registration Number: NCT06088797
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

Atypical developpement of spatial cognition has been shown in congenital bindness with some consequences on mathematic learning (Cattaneo et al., 2010) as well as on the mental representation of spatial maps (Thinus-Blanc \& Gaunet, 1997). This raises the issue of the role of vision in spatial abilities underlying mathematics and locomotion. These difficulties could also be found in case of partial visual deficiency, like very low visual acuity or large peripheral shrinkage of the visual field.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-10-05
• Study First Submitted QC: 2023-10-11
• Study First Posted: 2023-10-18
• Study Start: 2023-10-20
• Status Verified: 2024-03
• Last Update Submitted: 2024-03-04
• Last Update Posted: 2024-03-05
• Primary Completion: 2026-02-01
• Study Completion: 2026-02-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

For all :

• Aged 12 to 25
• Participant not opposed to the research and parents do not oppose participation in the protocol for minors

For healthy volunteers (normal sighted):

• with typical visual development with correction if needed

For participant with Visual Deficiencies:

• with congenital blindness
• or low visual acuity (between 1/10 and 3/10)
• or with visual field peripheral shrinkage (angle <20°).

Exclusion Criteria

• General knowledge and working memory skills with a standard score of less than 4
• neurological medical history
• Person deprived of liberty by judicial or administrative decision
• Person subject to a legal protection measure (tutorship, curatorship)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
healthy subjects	Mental imagery task	First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes
healthy subjects	WISC V Arithmetic subtest	First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes
healthy subjects	Proprioceptive spatial representation tasks	First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes
healthy subjects	WISC V Similarity and Span Test	First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes
low visual acuity	Tasks assessing number sense based on relative positions or lengths	First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes
reduced visual field	Proprioceptive spatial representation tasks	First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes
healthy subjects	Tasks assessing number sense based on relative positions or lengths	First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes
blind	Mental imagery task	First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes
blind	WISC V Arithmetic subtest	First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes
blind	WISC V Similarity and Span Test	First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes
reduced visual field	Tasks assessing number sense based on relative positions or lengths	First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes
blind	Proprioceptive spatial representation tasks	First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes
blind	Tasks assessing number sense based on relative positions or lengths	First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes
low visual acuity	Mental imagery task	First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes
low visual acuity	Proprioceptive spatial representation tasks	First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes
low visual acuity	WISC V Arithmetic subtest	First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes
reduced visual field	WISC V Arithmetic subtest	First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes
low visual acuity	WISC V Similarity and Span Test	First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes
reduced visual field	WISC V Similarity and Span Test	First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes
reduced visual field	Mental imagery task	First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes

Primary Outcome Measures

Name	Time	Method
percentage of correct responses	through study completion, an average of 2 year	The experimental tasks assess allocentric spatial representations in different modalities with correct responses to spatial vs non spatial questions for the Elementary Spatial Perception test and the mental imagery test.

Trial Locations

Locations (1)

Equipe Trajectoire du CRNL : INSERM U1028, CNRS UMR 5292; 🇫🇷 Lyon, France