Time Effect on the Predictability of Different Grafting for Gingival Recession RT 1

Not Applicable

Completed

• Conditions: Gingival Recession Types One(RT1)
• Interventions: Combination Product: melatonin with collagen matrix; Combination Product: connective tissue graft (CTG)

• Registration Number: NCT05976451
• Lead Sponsor: Ain Shams University

Brief Summary

The primary objective of this study was to evaluate time effect on the clinical predictability of collagen matrix Xenograft (CMX) with melatonin gel versus connective tissue graft (CTG) and determine whether it is proposed to be an alternative in multiple adjacent gingival recession (MAGR) in recession type one (RT1)

Detailed Description

this study was conducted to evaluate time effect on the clinical predictability of collagen matrix Xenograft (CMX) with melatonin gel versus connective tissue graft (CTG) and determine whether it is proposed to be an alternative in multiple adjacent gingival recession

Study Timeline

• Study Start: 2020-10-01
• Primary Completion: 2022-04-01
• Study Completion: 2023-03-03
• Study First Submitted: 2023-03-12
• Status Verified: 2023-07
• Study First Submitted QC: 2023-07-27
• Study First Posted: 2023-08-04
• Last Update Submitted: 2023-11-23
• Last Update Posted: 2023-11-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

• Presence of RT1 GRs of the maxillary or mandibular arch in the esthetic zone with a GR depth ≥2 mm,
• patients >18 years old,
• Full mouth plaque index score <20%
• Systemically and periodontally healthy patients.

Exclusion Criteria

• Smokers
• Patients with periodontitis stage III and IV were previous surgical treatment of GR,
• Pregnant or breastfeeding women; P
• Patients with para-functional habits or any source of occlusal trauma.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
collagen matrix	melatonin with collagen matrix	melatonin in collagen matrix with Modified Coronally Advanced Tunneling Technique (MCAT)
connective tissue graft (CTG)	connective tissue graft (CTG)	connective tissue graft with Modified Coronally Advanced Tunneling Technique (MCAT)

Primary Outcome Measures

Name	Time	Method
Recession depth	6-9 months	measure from CEJ to gingival margin by mm
interproximal clinical attachment level	6-9 months	measured from CEJ to base of pocket depth by using periodontal prob
Probing pocket depth (PPD)	6-9 months	from gingival margin to pocket depth measured by mm

Secondary Outcome Measures

Name	Time	Method
Keratinized tissue width	6-9 months	from free gingival groove to MGJ

Trial Locations

Locations (1)

Ain Shams University; 🇪🇬 Cairo, Al Qahirah, Egypt