Cardiac Performance Evaluation in Children With Steroid Dependent vs Steroid Resistant Nephrotic Syndrome
- Conditions
- Nephrotic Syndrome
- Interventions
- Device: Tissue Doppler imaging and Conventional Echocardiography
- Registration Number
- NCT06622915
- Lead Sponsor
- Sohag University
- Brief Summary
nephrotic syndrome (NS) is one of the most common pediatric kidney diseases There is an increased incidence of heart disease in patients with primary nephrotic syndrome (PNS) compared to the normal population Conventional Echocardiography is usually utilized to diagnose myocardial dysfunction. Tissue Doppler imaging is a non-invasive cardiac imaging technique which measures the velocity of the longitudinal motion of the mitral annulus, tricuspid annulus and the basal part of interventricular septum
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 60
-
Children with primary nephrotic syndrome.
- Age: 2 - 14 years.
- Both males and females
- Patients of primary cardiac diseases (e.g., congenital or rheumatic heart disease, cardio- myopathy).
Patients who refuse to give written informed consent to study
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description group A, Tissue Doppler imaging and Conventional Echocardiography steroid dependent nephrotic syndrome Group B Tissue Doppler imaging and Conventional Echocardiography steroid resistant nephrotic syndrome
- Primary Outcome Measures
Name Time Method cardiac performance evaluation in children with steroid dependent vs steroid resistant nephrotic syndrome 12 months compairing of myocardial performance index (MPI)(Tei index) in nephrotic dependant and resistant nephrotic syndrom by calculating ejection time (ET) of right and left ventricle and mitral closure time (MCT) using tissue doppler
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Sohag University hospitals
🇪🇬Sohag, Egypt