Cardiac Performance Evaluation in Children With Steroid Dependent vs Steroid Resistant Nephrotic Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- cardiac performance evaluation in children with steroid dependent vs steroid resistant nephrotic syndrome
研究概览
简要总结
nephrotic syndrome (NS) is one of the most common pediatric kidney diseases There is an increased incidence of heart disease in patients with primary nephrotic syndrome (PNS) compared to the normal population Conventional Echocardiography is usually utilized to diagnose myocardial dysfunction. Tissue Doppler imaging is a non-invasive cardiac imaging technique which measures the velocity of the longitudinal motion of the mitral annulus, tricuspid annulus and the basal part of interventricular septum
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 2 Years 至 14 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Children with primary nephrotic syndrome.
- •Age: 2 - 14 years.
- •Both males and females
排除标准
- •Patients of primary cardiac diseases (e.g., congenital or rheumatic heart disease, cardio- myopathy).
- •Patients who refuse to give written informed consent to study
结局指标
主要结局
cardiac performance evaluation in children with steroid dependent vs steroid resistant nephrotic syndrome
时间窗: 12 months
compairing of myocardial performance index (MPI)(Tei index) in nephrotic dependant and resistant nephrotic syndrom by calculating ejection time (ET) of right and left ventricle and mitral closure time (MCT) using tissue doppler
次要结局
未报告次要终点
研究者
Alaa yahia Mohamed
Resident of pediatric and neonatology department, Sohag University Hospitals
Sohag University