Effects of Empagliflozin on Post-Operative Atrial Fibrillatio
Phase 3
Recruiting
- Conditions
- atrial fibrillation.Unspecified atrial fibrillation and atrial flutterI48.9
- Registration Number
- IRCT20230110057098N1
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 492
Inclusion Criteria
patients older than 18 years of age
scheduled for elective coronary artery bypass graft surgery
patients who agree to receive treatment with empagliflozin
Exclusion Criteria
patients unwillingness to participate
history of diabetes mellitus
patients receiving empagliflozin for another indication
eGFR<30 ML/MIN
sever hepatic disease
history of ketoacidosis
history of atrial fibrillation
hystory of hypersensivity to empagliflozin or any excipients
patients who have participated in any other clinical trial
unstable or rapidly progressive renal disease
patients undergoing urgent surgery
unstable hemodynamic profile
history of recurrent uti
positive urine culture symptomatic abacteriuria asymptomatic bacteriuria
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Rate of post operative atrial fibrillation. Timepoint: Until the discharge day (max= 30 days). Method of measurement: Daily monitoring of 12-lead 24-hour ECG strips by resident physician.
- Secondary Outcome Measures
Name Time Method