Comparison of effect of two drugs used to reverse general anesthesia named sugammadex & neostigmine plus glycopyrrolate on higher mental functions in older adults undergoing hip surgeries

Not Applicable

• Conditions: Health Condition 1: O- Medical and SurgicalHealth Condition 2: M21- Other acquired deformities of limbs

• Registration Number: CTRI/2024/02/062288
• Lead Sponsor: Shreya Chauhan

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 4 March 2024

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Posted for elective hip surgeries under general anesthesia with ASA Physical Status one two three

Exclusion Criteria

Any neurological disorder affecting the patients ability to understand the questionnaire Patients with such visual or hearing impairment that it affects the patients ability to read

the scale or answer the questions that will be asked

Patients taking antidepressants and or tranquilisers Any known allergies to drug being administered Patient refusal

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the cognitive function using Postoperative Quality of Recovery <br/ ><br>Scale PQRS at 30min 12hrs 24hrs 72hrs 7th day and 30th day postoperatively from baseline <br/ ><br>values in patients receiving Sugammadex vs those receiving neostigmine plus glycopyrrolate <br/ ><br>combinationTimepoint: To compare the cognitive function using Postoperative Quality of Recovery <br/ ><br>Scale PQRS at 30min 12hrs 24hrs 72hrs 7th day and 30th day postoperatively

Secondary Outcome Measures

Name	Time	Method
To assess the hemodynamic adverse effects of sugammadex that is bradycardia and hypotension <br/ ><br>within 30 mins of its administration. <br/ ><br>To assess the total intraoperative opioid consumption. <br/ ><br>To assess the postoperative electrolytes levels within 24hrs.Timepoint: observe for bradycardia after 30 mins of reversal administration <br/ ><br>observe electrolytes after 24hrs