EUCTR2007-003666-17-GB
进行中（未招募）
不适用
The ATACAS Trial: Aspirin and Tranexamic Acid for Coronary Artery Surgery Trial - ATACAS
niversity Hospitals Bristol NHS Foundation Trust0 个研究点目标入组 2,400 人2007年9月14日
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- Ischamic heart disease operated
- 发起方
- niversity Hospitals Bristol NHS Foundation Trust
- 入组人数
- 2400
- 状态
- 进行中（未招募）
- 最后更新
- 13年前
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •males and females 18 years and older.
- •written informed consent.
- •elective coronary artery surgery.
- •Patient at increaed risk of major complications, defined by any of:
- •left ventricular ejection fraction impairment
- •Concomitant valvular or aortic surgery
- •aneurysmectomy
- •repeat cardiac surgery
- •chronic obstructive airways disease
- •renal impairment creatinine clearance 24\-45
排除标准
- •Poor English
- •Clinician preference for antifibrinolytic
- •urgent surgery for unstable symptoms
- •active peptic ulceration
- •allergy or contraindication to aspirin or tranexamic acid
- •aspirin therapy within 5 days of surgery
- •warfarin or clopidogril within 7 days of surgery
- •GIIb/IIIa antagonists within 24 hours
- •thrombocytopenia
- •severe renal impairment creatinine clearance \<25
结局指标
主要结局
未指定
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