Assessment the efficacy of Tranexamic Acid in reducing blood loss after laminectomy and postrolateral fusion of spine

Not Applicable

Recruiting

Conditions: Topical administration of TXA helps control bleeding and prevents unwanted side effects.
Spinal stenosis, lumbar region
M48.06

Registration Number: IRCT20120527009878N6

Lead Sponsor: Deputy of Research of Tabriz University

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 50

Inclusion Criteria

Patients with candidate laminectomy and fissure-medial fistula, who refer to Imam Reza Hospital in Tabriz
all patients aged 20 to 60 years

Exclusion Criteria

Use of anticoagulant drugs such as ASA and depiridamole
high PT, PTT, INR for any cause
history of any thrombotic event such as CVA and MI
history of bleeding disorders
history of TBI
history of CPR
kidney failure
OCP use, pregnancy Or lactation.
Also, patients who need blood transfusion before or during surgery for any reason

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Determination of the Effect of Tranexamic Acid on the Transfusion Level of Blood Transfusion in Patients under Laminectomy and Fibrous Fistula. Timepoint: During surgery and duration of hospitalization after surgery. Method of measurement: Blood volume injected to the patient in milliliters.;Determination of the Effect of Tranexamic Acid on the Length of Hospitalization During Laminectomy and Fistula. Timepoint: During surgery and duration of hospitalization after surgery. Method of measurement: Duration of hospitalization in hospital days.;Determine the effect of tranexamic acid on the amount of blood collected in hemovac in patients undergoing laminectomy and fissure of the posterolateral of the spine. Timepoint: duration of hospitalization after surgery. Method of measurement: The amount of blood accumulated in CC.

Secondary Outcome Measures