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Clinical Trials/NCT05406388
NCT05406388
Completed
Not Applicable

Ultrasound-guided Bilateral Erector Spinalis Plane Block on Postoperative Pain Management in Liver Transplantation Donors

Medipol University1 site in 1 country41 target enrollmentStarted: December 24, 2020Last updated:

Overview

Phase
Not Applicable
Status
Completed
Sponsor
Medipol University
Enrollment
41
Locations
1
Primary Endpoint
Opioid consumption

Overview

Brief Summary

Living donor liver transplantation has become a common treatment option for patients with end-stage liver disease. Donor hepatectomy is associated with significant postoperative pain due to inverted L-shaped incision. Therefore adequate analgesia is important for recovery.

Erector Spinae Plane Block (ESPB) is a safe anesthesia technique used to provide postoperative analgesia. This study aimed to compare the novel ultrasound-guided ESPB technique with controls in terms of postoperative opioid consumption and postoperative pain control on donor patients.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
Double (Participant, Outcomes Assessor)

Masking Description

The patient and the anesthesiologist who performs postoperative pain evaluation will not know the group.

Eligibility Criteria

Ages
18 Years to 65 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Donor patients scheduled for elective hepatectomy in liver transplantation surgery
  • Patients who are aged between 18-65

Exclusion Criteria

  • Patients who do not accept the procedure
  • Skin infection at the site of Erector Spina Plan Block area
  • Coagulation disorder or using anticoagulant drugs
  • Known local anesthetics and opioid allergy
  • Severe pulmonary and/or cardiovascular problems
  • Substance addiction or known psychiatric or mental problems
  • Chronic painkiller usage
  • Pregnancy or lactation

Outcomes

Primary Outcomes

Opioid consumption

Time Frame: Change from baseline opioid consumption at postoperative 0, 2, 4, 6, 12, 24, 36 and 48 hours

The amount of fentanyl required by the patient and given by the device will be recorded for the first 48 hours.

Secondary Outcomes

  • Visual Analog Scale(Change from baseline pain scores at postoperative 0, 2, 4, 6, 12, 24, 36 and 48 hours)

Investigators

Sponsor
Medipol University
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Tumay Uludag Yanaral

Assistant professor, MD

Medipol University

Study Sites (1)

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