The efficacy of elobixibat as bowel cleansing agent for bowel preparation before colonoscopy

Phase 4

• Conditions: require colonoscopy; colonoscopy

• Registration Number: JPRN-jRCTs041180026
• Lead Sponsor: Yamaguchi Daisuke

Brief Summary

The combination of elobixibat and 1-L PEG-Asc can be considered an alternative bowel preparation for colonoscopy considering the equivalent bowel cleansing effect and less frequent sleep disturbance.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-01-16
• Study Completion: 2020-03-31
• Results First Posted: 2021-05-10
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 210

Inclusion Criteria

adults at least 20 years of age

Exclusion Criteria

If they had any of the following conditions: ileus, suspected bowel obstruction or toxic megacolon; prior abdominal or pelvic surgery; inflammatory bowel disease; malignancy; severe cardiac disease (heart failure beyond NYHA Class III); chronic obstructive pulmonary disease, interstitial lung disease or uncontrolled asthma; renal failure and on dialysis, decompensated liver cirrhosis; coagulopathy or other hematologic disease with bleeding tendency; dementia or other cognitive disorders; or hypersensitivity to elobixibat. And if they were pregnant or breastfeeding.

Study & Design

• Study Type: Interventional
• Study Design: Not specified