NL-OMON42765
Completed
Not Applicable
ongitudinal analysis of head and neck cancer-specific immunity in patients treated with (salvage) surgery - Tumor-specific immunity in HNSCC treated with surgery
Antoni van Leeuwenhoek Ziekenhuis0 sites60 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- head and neck cancer
- Sponsor
- Antoni van Leeuwenhoek Ziekenhuis
- Enrollment
- 60
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •a. Histologically proven HPV positive or negative HNSCC with an indication for (salvage) surgery with/without adjuvant (C)RT in a curative setting
- •b. Tumor site: oral cavity, and in case of salvage surgery: all sites
- •c. Age above 18 years
- •d. Performance score WHO 0,1 or 2 at time of study entry
- •e. Written ICF
Exclusion Criteria
- •a. The use of immunosuppressive drugs at start of the treatment
- •b. Anemia \< 6\.0 mmol/L
- •c. In case of disease relapse or progression: Any bleeding disorder or anti\-coagulation therapy, that cannot be discontinued or corrected, that significantly increases the risk of a bleeding due to the biopsy.
Outcomes
Primary Outcomes
Not specified
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