The ACL SNNAP Trial: ACL surgery necessity in non acute patients

Not Applicable

Completed

• Conditions: Specialty: Musculoskeletal disorders, Primary sub-specialty: Elective orthopaedic surgery; UKCRC code/ Disease: Musculoskeletal/ Other disorders of the musculoskeletal system and connective tissue; Musculoskeletal Diseases; Anterior cruciate ligament deficiency

• Registration Number: ISRCTN10110685
• Lead Sponsor: niversity of Oxford

Brief Summary

2020 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/32410697 protocol (added 18/05/2020) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35988569/ (added 22/08/2022) 2024 Results article in https://pubmed.ncbi.nlm.nih.gov/38940695/ (added 01/07/2024)

Detailed Description

Not available

Study Timeline

• Study Start: 2016-11-16
• Study Completion: 2021-09-11
• Last Update Posted: 15 July 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 316

Inclusion Criteria

1. Participant is willing and able to give informed consent for participation in the study
2. Male or Female, aged 18 years or above
3. Symptomatic ACL deficiency (instability-episodes of frank giving way or feeling unstable) with ACL deficiency confirmed using clinical assessment and MRI scan

Exclusion Criteria

1. Less than 4 months since injury
2. Previous knee surgery (other than diagnostic arthroscopy)to index knee, concomitant severe injury to contra-lateral knee
3. Meniscal pathology considered sufficiently symptomatic to require surgery i.e. locked knee, large bucket handle cartilage tear
4. Knee joint status is grade 3-4 on the Kellgren and Lawrence scale
5. Inflammatory arthropathy
6. Grade 3 MCL/LCL injury, associated PCL/PLC injury
7. Pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Knee injury and Osteoarthritis Outcome Score (KOOS4) is meaured at at baseline, 6, 12 and 18 months.