Comparison of the clinical and cost effectiveness of two management strategies for non-acute Anterior Cruciate Ligament (ACL) injury: Rehabilitation versus surgical Reconstruction

niversity of Oxford0 个研究点目标入组 316 人开始时间: 2016年11月16日最近更新: 2024年7月15日

适应症

试验速览

2020 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/32410697 protocol (added 18/05/2020) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35988569/ (added 22/08/2022) 2024 Results article in https://pubmed.ncbi.nlm.nih.gov/38940695/ (added 01/07/2024)

•1. Participant is willing and able to give informed consent for participation in the study
•2. Male or Female, aged 18 years or above
•3. Symptomatic ACL deficiency (instability-episodes of frank giving way or feeling unstable) with ACL deficiency confirmed using clinical assessment and MRI scan

•1. Less than 4 months since injury
•2. Previous knee surgery (other than diagnostic arthroscopy)to index knee, concomitant severe injury to contra-lateral knee
•3. Meniscal pathology considered sufficiently symptomatic to require surgery i.e. locked knee, large bucket handle cartilage tear
•4. Knee joint status is grade 3-4 on the Kellgren and Lawrence scale
•5. Inflammatory arthropathy
•6. Grade 3 MCL/LCL injury, associated PCL/PLC injury
•7. Pregnancy

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