NL-OMON29148尚未招募不适用
Evaluation of pharmacokinetic and –dynamic characteristics of norepinephrine for the augmentation of arterial blood pressure in healthy volunteers prior to and during general anesthesia
niversity Medical Center Groningen, dept of Anaesthesiology0 个研究点目标入组 36 人开始时间: 待定最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 36
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •?American Society of Anesthesiologists (ASA) Physical Status I or II
- •?No exclusion criterion is present
- •?Informed, and willing to give written informed consent.
排除标准
- •?Refusal of the volunteer to participate
- •?Diseases involving the cardiovascular system (hypertension, coronary artery disease, prior acute myocardial infarction, any valvular and/or myocardial disease involving decrease in ejection fraction, arrhythmias, which are either symptomatic or require continuous medication/pacemaker/automatic internal cardioverter defibrillator)
- •?A difference > 15 mmHg in measured systolic or diastolic blood pressure value (SBP, DBP) between the left and right upper arm, as determined by non-invasive cuff oscillometry during the screening visit.
- •?An increased risk of difficult mask ventilation or tracheal intubation, as judged by the anesthesiologist-researcher.
- •?Pulmonary disease
- •?Gastric or endocrinologic diseases
- •?End-stage liver or kidney failure
- •?Use of tricyclic antidepressive medication or MAO inhibitors.
研究者
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